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Name of Project: A 12-Year Follow-up of a Cocaine-Dependent Sample

Principal Investigator: Yih-Ing Hser, Ph. D.

Co-Principal Investigators: Elena Stark, M.D., Alfanso Parades, M.D., Richard Rawson, Ph.D., and M. Douglas Anglin, Ph.D.

Funding Agency: National Institute on Drug Abuse (NIDA)

Funding Period: September 2000-July 2004

Scope of Project: This study is a 12-year follow-up of 321 cocaine-dependent men who were originally admitted in 1988-1989 to the West Los Angeles Veterans Affairs Medical Center. These patients were interviewed at intake and in two follow-up interviews conducted in 1990-1991 and 1991-1992 as part of a NIDA-funded study. Their cocaine-use careers from onset of use to treatment entry averaged 11.5 years. The natural history database established by the previous interviews will be supplemented with data from almost 12 years after treatment admission. The aims of the study are: (1) to provide a detailed natural history description of approximately 24-year-long cocaine-use careers of cocaine-dependent men; (2) to identify factors that influence relapse and cessation of use over the course of the cocaine use career; (3) to analyze and describe morbidity and mortality among this sample; (4) to evaluate the extent of criminal activity, identify specific criminal career patterns in relation to cocaine use, and to assess patterns of institutionalization and legal supervision over the cocaine use career and their effects; (5) to analyze the history of treatment intervention and assess the effects of specific and cumulative treatment episodes on cocaine use. The study will inform policy and strategies for treating cocaine use by improving the understanding of long-term patterns and consequences of cocaine and other drug use, utilization of drug treatment and other social interventions, and the associated outcomes of such drug use and treatment.


For more information, contact Yih-Ing Hser.

Last updated - 08/14/2003

Last reviewed - 08/13/2003

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